| Th.ise book includes chapters on the transport of other molecules by the SLC26 family, including oxalate in the kidney and sugars in cochlear hair cells amongst others. It also describes recent discoveries that most SLC26 transporters bind to scaffold proteins and that they all contain a conserved domain predicted to participate in protein-protein interactions. These suggest the SLC26 transporters exist in complexes with other Cl- and HCO3- transporters, and possibly other regulatory proteins. This book explores the functional role of these interactions, leading to better understanding of transepithelial fluid and electrolyte secretion and the diseases associated with it. |
|
| |
| Binding: Hardcover |
| Specs: 284 pages | 1.31 Lbs |
| ISBN: 0470016248 |
| ISBN-13: 9780470016244 |
| Edition: 1 |
| Publisher: John Wiley and Sons, Incorporated | Publish Date 09/06 | Copyright 2006 |
| Series: Novartis Foundation Symposium |
| Volume: 273 |
| Format: Proceedings Mar '05 |
| |
|
| |
|
|